Medical, Socialogical and environmental issues in cardiovascular disease epidemiology, prevention and rehabilitation.
POTENTIAL GAIN IN LIFE EXPECTANCY WITH CONTROL OF CARDIOVASCULAR DISEASE IN INDIA
A CASE STUDY FROM GOA STATE
MS Kulkarni, AMA Ferreira, DD Motghare
Department of Preventive and Social Medicine, Goa Medical College, Bambolim, Goa INDIA
 
  ABSTRACT
 
Cardiovascular disease has become a major cause of morbidity and mortality in developing countries including India. The present study was conducted to find out the potential gain in average years of life due to prevention of mortality related to diseases of cardiovascular system. The study was based on complete records of registered mortality in the state of Goa as per ICD-9 classification for the year 1991. The gain in life expectancy at birth measured using cause elimination life table technique. When mortality due to cardiovascular diseases was eliminated the life expectancy at birth increased by 12.95(18.86%) years for entire population, 11.5(17.81) years for male and 15.23(20.73%) for females. This has an important implication for developing countries, which are in the process of epidemiological transition from communicable to noncommunicable diseases.
 
 INTRODUCTION
 
Many developing countries including India are undergoing epidemiological transition from communicable to non-communicable diseases, which brought about a decline in crude death rate and a surge in life expectancy. The leading causes of death now faced by these countries are cardiovascular diseases, accidents, injury, neoplasm etc, which are largely preventable.
 
Table 1: Life Expectancy of the Goa Population in 1991
 
Age Male Female Total
0 64.6 73.5 68.7
1 65.0 73.6 69.0
5 61.5 70.1 65.5
15 51.9 60.4 55.8
25 42.5 50.8 46.4
35 33.8 41.5 37.4
45 25.5 32.2 28.7
55 18.6 23.4 21.0
65 13.0 15.6 14.4
70 10.8 12.5 11.7
 
In this research article, an attempt has been made to estimate the gain in life expectancy, should mortality due to cardiovascular diseases be eliminated, by using cause elimination life table technique. The life tables are routinely used to study mortality experience of a cohort. The expectation of life at birth reflects the number of years a person is expected to survive under existing conditions while expectation of life at various ages indicates the average number of years of life remaining at attainment of the given age. The article seeks to study the gain in average year of life at birth at various ages due to prevention of cardiovascular disease.
 
 MATERIAL AND METHODS
 
The data for the present study has been obtained from the records on Registration of Births and Deaths for the State of Goa for the year 19912 . The registration of vital events in Goa is almost 100% and more than 90% of deaths are medically certified. The ninth revised International Classification of Disease (ICD-9) including codes 390-459 was used for classification of deaths pertaining to cardiovascular diseases while 1991 census population of Goa was used to compute the age and sex specific mortality rates to compute life table by Greville's method. The cause elimination life table technique was used to find the gain in life expectancy following elimination of deaths due to cardiovascular diseases and involve the following steps3.
 
1. First a conventional abridged life table was constructed.
2. Then cause elimination life table was obtained by constructing a life table devoid of mortality due to cardiovascular disease.
3. Expectation of life at various ages was computed for the hypothetical situation in which this cause of death was assumed as eliminated.
 
Table 2: Cause-eliminated life expectancy due to cardiovascular diseases in the Goa Population
 
Age Male Female Total
0 76.1 88.7 81.6
1 76.8 89.0 82.2
5 73.3 85.6 78.7
15 63.6 75.9 59.6
25 54.3 66.4 50.8
35 45.8 57.1 42.2
45 37.8 47.8 34.6
55 31.1 39.0 34.6
65 25.7 30.1 28.5
70 23.4 27.9 25.8
 
 RESULTS AND DISCUSSION
 
The crude death rate for Goa for the year 1991 was 6.74/1000 population. It was higher for males (7.97/1000) than females (5.46/1000). The cause specific death rate due to cardiovascular disease was 253.89 per 100000 population with higher mortality due to cardiovascular disease among males (286.15/100000 population) compared to females (220.52/100000 population).
 
The life expectancy at birth was 65.67 years for males and 73.46 years for female, while the combined life expectancy was 68.68 years for the year 1991(Table-1). The life expectancy was consistently higher for females at all age groups.
 
The cause eliminated life table constructed by eliminating all deaths due to cardiovascular disease showed the life expectancy at birth to be 81.63 years for combined population; 76.07 years for males and 88.69 years for females (Table 2).
 
The potential gain in life expectancy at birth following elimination of cardiovascular diseases was estimated 12.95 years (18.86%) in the combined population (Table 3). In terms of absolute number of years the gain in life expectancy would be about 13 years for population aged above one year. For males, the potential gain in life expectancy at birth due to prevention of cardiovascular diseases in adult life would be 11.50 years (17.81%). The net gain would be around 12 years for ages above 34 years. Likewise, for females, the potential gain in life expectancy at birth due to control of cardiovascular disease would be 15.24 years (20.74%). The net gain in the life expectancy at subsequent ages would be 15.5 years.
 
In the United States of America, Tsai et al (1978)4 estimated that elimination of cardiovascular disease would result in addition to expectation of life at birth of 12.36 years for combined population, 11.10 years for white males and 10.74 years for non-white males. For white females the gain in life expectancy was 12.81 years and 15.66 years for non-white females. Krishnan Namboodari and Suchindran C.M.5 reported the gain in life expectancy at age 65 years attributed to eliminating cardiovascular disease was 12.61 years.
 
Table 3: Potential gain in life expectancy due to cardiovascular disease
 
Age Male Female Total
0 11.5 (17.8) 15.2 (20.7) 13.0 (18.9)
1 11.7 (18.0) 15.4 (21.0) 13.2 (19.1)
5 11.8 (19.1) 15.5 (22.1) 13.2 (20.2)
15 11.8 (22.7) 15.5 (25.7) 13.3 (23.7)
25 11.8 (27.8) 15.6 (30.6) 13.3 (28.6)
35 12.0 (35.5) 15.6 (37.7) 13.4 (35.9)
45 12.2 (47.9) 15.7 (48.7) 13.5 (47.2)
55 12.5 (67.4) 15.6 (66.5) 13.6 (65.0)
65 12.7 (97.9) 15.4 (98.3) 14.1 (97.9)
70 12.6 (116.5) 15.5 (124.2) 14.1 (120.6)
 
  CONCLUSIONS
 
This study was conducted to estimate the potential gain in life expectancy when mortality due to cardiovascular diseases is eliminated. The present study showed that the net gain in life expectancy at birth would be 18.86% years and this gain is higher among females than males. Such life tables are adjusted for the impact of differential risks of dying from other causes that operates in the various subgroups. The particular technique serves as a useful tool to gauge the potential benefits of cause elimination in both developed and the developing countries in planning health services.
 
  REFERENCES
 
1. Omran AR: The epidemiologic transition: a theory of the epidemiology of population change. Millbank Mem Fund Q 1971; 49, 509-538.
2. Office of the Chief Registrar of Birth and Deaths, Government of Goa, Panaji, Goa. Annual report on registration of birth and deaths. 1991.
3. Suchindran CM, Koo HP. Demography and Public health. Oxford Textbook Public Health. 3rd Ed. pp. 829-848.
4. Tsai SP, Lee ES, Hardy RJ .The effects of a reduction in leading causes of death: potential gain in life expectancy. Am J Public Health 1978; 68: 966-71.
5. Namboodari K, Suchindran CM . Textbook on life table techniques and their applications. Chapter 6- Multiple Decrement Life Tables. Academic Press. 1987 pp.92-105.